How do I clear the cache in Office 2016?.How do I clear the cache in Office 365?.How do I fix Microsoft Office Upload Center found a problem?.How do I turn off Microsoft Office cache?.To fix this problem, try manually deleting your Microsoft Office Document Cache.
You'll see an alert in your status bar that says the Microsoft Office Document Cache encountered a problem, with a link to repair. When cache file corruption happens, your file will seem to be stuck in the Office Upload Center.